| Weight | 231.086 g/mol |
|---|---|
| Formula | C8H8Cl2N4 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
guanabenz (5051-62-7)
Wytensin · Guanabenz Acetate · BR 750
Score:
#412 in Neuroscience
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#672 in Biochemistry
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#1884 in Biology
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#2271 in Chemistry
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- Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. (PLOS ONE, 2008)
- Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. (Drugs, 1983)
- Guanabenz-mediated Inactivation and Enhanced Proteolytic Degradation of Neuronal Nitric-oxide Synthase (Journal of Biological Chemistry, 2000)
- Guanabenz, guanochlor, guanoxan and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes (European Journal of Pharmacology, 1989)
- Studies on the centrally mediated hypotensive activity of guanabenz. (European Journal of Pharmacology, 1976)
- Renal effects of the antihypertensive, guanabenz, in the dog. (Journal of Pharmacology and Experimental Therapeutics, 1982)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Wytensin
- Guanabenz Acetate
- BR 750
- BR-750
- 2,6-Dichlorobenzylideneaminoguanidine
- BR750
- Wyeth Ayerst of Guanabenz Acetate
- WY-8678
- WY 8678
- 2,6 Dichlorobenzylideneaminoguanidine
- Wyeth-Ayerst of Guanabenz Acetate
- Guanabenz Monoacetate
- WY8678
- Guanabenz Acetate Wyeth-Ayerst
-
SMILESC1=CC(=C(C(=C1)Cl)C=NN=C(N)N)Cl
-
InChIKeyWDZVGELJXXEGPV-UHFFFAOYSA-N
- Pubchem - guanabenz
- Wikipedia - guanabenz
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension). The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
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guanabenz
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