Weight | 328.412 g/mol |
---|---|
Formula | C19H24N2O3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 4 |
Aromatic Rings | 2 |
Rotatable Bonds | 8 |
labetalol (36894-69-6)
Normodyne · Trandate · Labetolol
Score:
#48 in Neurology
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#250 in Neuroscience
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#1151 in Biology
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#1308 in Chemistry
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- Influence of labetalol on cocaine-induced coronary vasoconstriction in humans (The American Journal of Medicine, 1993)
- Letter: Intravenous labetalol in severe hypertension. (The Lancet, 1975)
- A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy (Obstetrics & Gynecology, 1987)
- A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy (American Journal of Obstetrics and Gynecology, 1990)
- A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. (British Journal of Clinical Pharmacology, 1976)
- Labetalol Reduces Iodine-131 MIBG Uptake by Pheochromocytoma and Normal Tissues (The Journal of Nuclear Medicine, 1989)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Normodyne
- Trandate
- Labetolol
- Labetalol Hydrochloride
- Dilevalol
- AH 5158
- Labetalol, (R,R)-Isomer
- R,R Labetalol
- Presolol
- Apo Labetalol
- Apo-Labetalol
- ApoLabetalol
- AH-5158
- AH5158
- Albetol
- SCH 19927
- SCH-19927
- R,R-Labetalol
- SCH19927
-
SMILESCC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O
-
InChIKeySGUAFYQXFOLMHL-UHFFFAOYSA-N
- Pubchem - labetalol
- Wikipedia - labetalol
Labetalol is a medication used to treat high blood pressure. It can be given intravenously in severe hypertensive situations, or by mouth for long term hypertension management. Its dose and use is limited by its main side effectpostural hypotension, where there is a substantial drop in blood pressure when standing up.
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Synthesis
Reactant
+
Benzene, (3-chlorobutyl)
(Alkylation of primary amines)
Reactant
+
1-Methyl-3-phenylpropylamine
(Reductive amination)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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