| Weight | 405.495 g/mol |
|---|---|
| Formula | C21H31N3O5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 12 |
lisinopril
Zestril · Prinivil · MK-521
77726-95-5, 76547-98-3, 83915-83-7
Score:
#284 in Biochemistry
,
#1076 in Biology
,
#1206 in Chemistry
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- Sigma-Aldrich - Search for lisinopril
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- TCI - lisinopril66.00 - 200.00 USD
- Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study (BMJ, 2000)
- Comparative Effects of Low and High Doses of the Angiotensin-Converting Enzyme Inhibitor, Lisinopril, on Morbidity and Mortality in Chronic Heart Failure (Circulation, 1999)
- Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes (The Lancet, 1998)
- Lisinopril-Mediated Regression of Myocardial Fibrosis in Patients With Hypertensive Heart Disease (Circulation, 2000)
- Crystal Structure of the Human Angiotensin-Converting Enzyme-Lisinopril Complex (Nature, 2003)
- Randomised placebo-controlled trial of lisinopril in normotensive patients with insulin-dependent diabetes and normoalbuminuria or microalbuminuria (The Lancet, 1997)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Zestril
- Prinivil
- MK-521
- Lisinopril Maleate (1:1)
- Lisinopril Sulfate (1:2)
- Lysinopril
-
SMILESC1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O
-
InChIKeyRLAWWYSOJDYHDC-UHFFFAOYSA-N
- Pubchem - lisinopril
- Wikipedia - lisinopril anhydrous
Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class used primarily in treatment of high blood pressure, heart failure, and after heart attacks. It is also used for preventing kidney and eye complications in people with diabetes. Its indications, contraindications, and side effects are as those for all ACE inhibitors.
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Synthesis
DL-Homophenylalanine
+
Reactant
(Alkylation of primary amines)
Reactant
+
L-proline
(Schotten-Baumann amide from acid)
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lisinopril
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