| Weight | 477.048 g/mol |
|---|---|
| Formula | C29H33ClN2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
loperamide (53179-11-6)
Imodium · Loperamide Hydrochloride · Loperamide Monohydrochloride
Score:
#529 in Biology
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#562 in Chemistry
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- Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles (Pharmaceutical Research, 1997)
- Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency (Digestive Diseases and Sciences, 1982)
- Irinotecan (CPT-11) High-Dose Escalation Using Intensive High-Dose Loperamide to Control Diarrhea (Journal of the National Cancer Institute, 1994)
- Role of loperamide and placebo in management of irritable bowel syndrome (IBS) (Digestive Diseases and Sciences, 1984)
- Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. (Anesthesiology, 2002)
- Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123. (Journal of Controlled Release, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Imodium
- Loperamide Hydrochloride
- Loperamide Monohydrochloride
- R 18553
- R-18553
- R18553
-
SMILESCN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4
-
InChIKeyRDOIQAHITMMDAJ-UHFFFAOYSA-N
- Pubchem - loperamide
- Wikipedia - loperamide
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
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Estimated Properties
| Boiling Point | 417.44 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.2 g/cm3 | EPA T.E.S.T. |
| Flash Point | 317.33 C | EPA T.E.S.T. |
| Water Solubility | 5.6 mg/L | EPA T.E.S.T. |
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