Weight | 241.243 g/mol |
---|---|
Formula | C11H15NO5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 6 |
methocarbamol (532-03-6)
Robaxin · Ortoton · Guaiphenesin Carbamate
Score:
#61 in Neurology
,
#304 in Neuroscience
,
#1369 in Biology
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#1602 in Chemistry
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- SIMULTANEOUS DETERMINATION OF PARACETAMOL AND METHOCARBAMOL IN TABLETS BY RATIO SPECTRA DERIVATIVE SPECTROPHOTOMETRY AND LC (Journal of Pharmaceutical and Biomedical Analysis, 2001)
- Corrosion Inhibition and Adsorption Properties of Methocarbamol on Mild Steel in Acidic Medium (Portugaliae Electrochimica Acta, 2009)
- Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability. (Journal of Pharmacology and Experimental Therapeutics, 1992)
- A Comparison of Calcium Gluconate and Methocarbamol (Robaxin) in the Treatment of Latrodectism (Black Widow Spider Envenomation) (American Journal of Tropical Medicine and Hygiene, 1981)
- Evaluation of the abuse potential of methocarbamol. (Journal of Pharmacology and Experimental Therapeutics, 1989)
- Packed column supercritical fluid chromatographic separation and estimation of acetaminophen, diclofenac sodium and methocarbamol in pharmaceutical dosage forms (Talanta, 1998)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - Robaxin
- Ortoton
- Guaiphenesin Carbamate
- Lumirelax
- Parabaxin
-
SMILESCOC1=CC=CC=C1OCC(COC(=O)N)O
-
InChIKeyGNXFOGHNGIVQEH-UHFFFAOYSA-N
- Pubchem - methocarbamol
- Wikipedia - methocarbamol
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under the trade name Robaxin, it is marketed by Actient Pharmaceuticals in the United States and Pfizer in Canada. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase.
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Synthesis
CARBAMIC ACID
+
Reactant
(Ester from carboxilic acid(SN2))
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
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