| Weight | 240.303 g/mol |
|---|---|
| Formula | C12H20N2O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
PIRBUTEROL (38677-81-5)
Maxair · pirbuterol acetate · CP-24,314-1
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- Decreased Lymphocyte Beta-Adrenergic-Receptor Density in Patients with Heart Failure and Tolerance to the Beta-Adrenergic Agonist Pirbuterol (The New England Journal of Medicine, 1981)
- Pirbuterol, an oral beta-adrenergic receptor agonist, in the treatment of chronic cardiac failure. (Circulation, 1982)
- Effects of in vivo -adrenoceptor down-regulation on cardiac responses to prenalterol and pirbuterol (Journal of Cardiovascular Pharmacology, 1983)
- Hemodynamic effects of oral pirbuterol in chronic severe congestive heart failure. (Circulation, 1981)
- Use of a hand-held, metered-dose aerosol delivery device to administer pirbuterol acetate to horses with 'heaves' (Equine Veterinary Journal, 1996)
- Pirbuterol, a selecttve beta2 adrenergic bronchodilator. (Journal of Pharmacology and Experimental Therapeutics, 1978)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Maxair
- pirbuterol acetate
- CP-24,314-1
- 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-tert-butylamino ethyl)pyridine, dihydrochloride
- CP 24315-1
- pirbuterol dihydrochloride
- pyrbuterol
- CP-24315-1
- 3M brand of pirbuterol acetate
- pirbuterol acetate salt
- pirbuterol sulfate
-
SMILESCC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O
-
InChIKeyVQDBNKDJNJQRDG-UHFFFAOYSA-N
- Pubchem - PIRBUTEROL
- Wikipedia - pirbuterol
Pirbuterol (trade name Maxair) is a short-acting 2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler (Maxair Autohaler).
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Synthesis
Tert-butylboronic Acid
+
Reactant
(Chan-Lam coupling reaction)
Reactant
+
2-Chloro-2-methylpropane
(Alkylation of primary amines)
Reactant
+
tert-Butylamine
(Reductive amination)
2-(hydroxymethyl)pyridin-3-ol
+
Reactant
(Friedel-Crafts alkylation)
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