| Weight | 316.485 g/mol |
|---|---|
| Formula | C21H32O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
pregnenolone (145-13-1)
5 Pregnen 3 beta ol 20 one · 5-Pregnen-3-beta-ol-20-one
Score:
#745 in Neuroscience
,
#1363 in Biochemistry
,
#3297 in Biology
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#4115 in Chemistry
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- Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017 and P450 aromatase localized in neurons (Proceedings of the National Academy of Sciences of the United States of America, 2004)
- Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. (Molecular Pharmacology, 1991)
- Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it. (Proceedings of the National Academy of Sciences of the United States of America, 1992)
- Pregnenolone and its sulfate ester in the rat brain (Brain Research, 1983)
- Neurosteroids: Biosynthesis of Pregnenolone and Progesterone in Primary Cultures of Rat Glial Cells* (Endocrinology, 1989)
- Pregnenolone-sulfate: an endogenous antagonist of the -aminobutyric acid receptor complex in brain? (Brain Research, 1987)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 5 Pregnen 3 beta ol 20 one
- 5-Pregnen-3-beta-ol-20-one
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SMILESCC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
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InChIKeyORNBQBCIOKFOEO-UHFFFAOYSA-N
- Pubchem - pregnenolone
- Wikipedia - pregnenolone
Pregnenolone (P5), or pregn-5-en-3-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
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pregnenolone
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