| Weight | 352.471 g/mol |
|---|---|
| Formula | C20H32O5 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 12 |
prostaglandin D2 (41598-07-6)
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#626 in Neuroscience
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#1083 in Biochemistry
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#2796 in Biology
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#3503 in Chemistry
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- Sigma-Aldrich - prostaglandin D2146.00 - 577.00 USD
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- Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. (Journal of Experimental Medicine, 2001)
- Prostaglandin D2 as a Mediator of Allergic Asthma (Science, 2000)
- Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. (Journal of Immunology, 1982)
- Release of prostaglandin D2 into human airways during acute antigen challenge (The New England Journal of Medicine, 1986)
- Increased Production of Prostaglandin D2 in Patients with Systemic Mastocytosis (The New England Journal of Medicine, 1980)
- 15-Deoxy-12,14-prostaglandin J2 A PROSTAGLANDIN D2 METABOLITE GENERATED DURING INFLAMMATORY PROCESSES (Journal of Biological Chemistry, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)O)O
-
InChIKeyBHMBVRSPMRCCGG-UHFFFAOYSA-N
- Pubchem - prostaglandin D2
- Wikipedia - prostaglandin D2
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by mast cells recruits Th2 cells, eosinophils, and basophils. In mammalian organs, large amounts of PGD2 are found only in the brain and in mast cells.
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