Weight | 364.529 g/mol |
---|---|
Formula | C25H32O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
QUINESTROL (152-43-2)
Estrovis · Ethinyl Estradiol 3 Cyclopentyl Ether · Ethinyl Estradiol 3-Cyclopentyl Ether
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- Allergic reaction to quinestrol. (BMJ, 1970)
- Antifertility effect of levonorgestrel and quinestrol in Brandt's voles (Lasiopodomys brandtii) (Integrative Zoology, 2007)
- Effects of chronic oral administration of a long-acting estrogen, quinestrol, to dogs (Toxicology and Applied Pharmacology, 1969)
- Clinical Study of a Once-a-Month Oral Contraceptive: Quinestrol-Quingestanol * (Fertility and Sterility, 1970)
- Inclusion of quinestrol and 2,6-di-O-methyl--cyclodextrin: Preparation, characterization, and inclusion mode. (Carbohydrate Polymers, 2013)
- Selective Colorimetric Determination of Microgram Amounts of Quinestrol and Ethinyl Estradiol in Dosage Forms (Journal of Pharmaceutical Sciences, 1967)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Estrovis
- Ethinyl Estradiol 3 Cyclopentyl Ether
- Ethinyl Estradiol 3-Cyclopentyl Ether
- Parke Davis Brand of Quinestrol
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SMILESCC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC5CCCC5
-
InChIKeyPWZUUYSISTUNDW-UHFFFAOYSA-N
- Pubchem - QUINESTROL
- Wikipedia - quinestrol
Quinestrol (INN, USAN, BAN) (brand names Agalacto-Quilea, Basaquines, Eston, Estrovis, Estrovister, Plestrovis, Qui-Lea), also known as ethinylestradiol 3-cyclopentyl ether (EE2CPE), is a synthetic, steroidal estrogen which is used in menopausal hormone therapy and occasionally to treat breast cancer and prostate cancer. It is a prodrug of ethinylestradiol (with cyclopentanol also being formed) with no intrinsic estrogenic activity of its own, and has a very long terminal half-life of more than 120 hours due to enhanced lipophilicity. Because of its much longer terminal half-life, quinestrol is two to three times as potent as ethinylestradiol.
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