Weight | 473.594 g/mol |
---|---|
Formula | C28H27NO4S |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 2 |
Aromatic Rings | 4 |
Rotatable Bonds | 7 |
raloxifene (84449-90-1)
Score:
#226 in Neuroscience
,
#273 in Biochemistry
,
#1057 in Biology
,
#1180 in Chemistry
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- Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene Results From a 3-Year Randomized Clinical Trial (JAMA, 1999)
- The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial (JAMA, 1999)
- Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. (The New England Journal of Medicine, 1997)
- Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. (JAMA, 1999)
- Effects of Tamoxifen vs Raloxifene on the Risk of Developing Invasive Breast Cancer and Other Disease Outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 Trial (JAMA, 2006)
- Effects of Raloxifene on Cardiovascular Events and Breast Cancer in Postmenopausal Women (The New England Journal of Medicine, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O
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- Pubchem - raloxifene
- Wikipedia - raloxifene
Raloxifene, sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer. It is taken by mouth. Side effects of raloxifene include hot flashes, leg cramps, and an increased risk of blood clots and other cardiovascular events such as stroke.
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