| Weight | 529.786 g/mol |
|---|---|
| Formula | C32H53N2O4+ |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
Rocuronium (119302-91-9, 143558-00-3)
Score:
#999 in Biochemistry
,
#2629 in Biology
,
#3283 in Chemistry
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- Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. (Anesthesiology, 1993)
- A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. (Angewandte Chemie, 2002)
- Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study. (Anesthesiology, 2006)
- Rocuronium versus succinylcholine for rapid sequence induction intubation. (Cochrane Database of Systematic Reviews, 2015)
- First Human Exposure of Org 25969, a Novel Agent to Reverse the Action of Rocuronium Bromide (Anesthesiology, 2005)
- Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine. (Anesthesiology, 2008)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C
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InChIKeyYXRDKMPIGHSVRX-UHFFFAOYSA-N
- Pubchem - Rocuronium
- Wikipedia - rocuronium
Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. It is used for both standard endotracheal intubation and rapid sequence induction (RSI), although suxamethonium chloride is usually selected for RSI given its fast onset of action compared with rocuronium.
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