Weight | 361.31 g/mol |
---|---|
Formula | C14H30Cl2N2O4 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 9 |
Succinylcholine chloride (71-27-2)
Succinylcholine · Suxamethonium · Anectine
Score:
#395 in Neuroscience
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#1785 in Biology
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#2125 in Chemistry
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- Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. (Anesthesiology, 1993)
- Pathophysiology of hyperkalemia induced by succinylcholine. (Anesthesiology, 1975)
- Succinylcholine -induced hyperkalemia in acquired pathologic states : Etiologic factors and molecular mechanisms (Anesthesiology, 2006)
- Critical Hemoglobin Desaturation Will Occur before Return to an Unparalyzed State following 1 mg/kg Intravenous Succinylcholine (Anesthesiology, 1997)
- Rocuronium versus succinylcholine for rapid sequence induction intubation. (Cochrane Database of Systematic Reviews, 2015)
- Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine (Pharmacology & Therapeutics, 1990)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Succinylcholine
- Suxamethonium
- Anectine
- Quelicin
- Succinyldicholine
- Suxamethonium Chloride
- Succinylcholine Iodide
- Succinylcholine Diperchlorate
- Suxamethonium Bromide
- Lysthenon
- Ditilin
- Celocurine
- Listenon
- Succinylcholine Dichloride
- Succinylcholine Diiodide
- Succinylcholine Dichloride, Di H2O
- Myorelaxin
- Succicuran
- Succinylcholine Dibromide
- Succinylcholine Dichloride, Di-H2O
-
SMILESC[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]
-
InChIKeyYOEWQQVKRJEPAE-UHFFFAOYSA-L
- Pubchem - Succinylcholine chloride
- Wikipedia - succinylcholine chloride
Suxamethonium chloride, also known as suxamethonium or succinylcholine, is a medication used to cause short-term paralysis as part of general anesthesia. This is done to help with tracheal intubation or electroconvulsive therapy. It is given either by injection into a vein or muscle.
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Synthesis
Reactant
+
choline
(O-acylation)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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