| Weight | 225.288 g/mol |
|---|---|
| Formula | C12H19NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
terbutaline (46719-29-3, 23031-25-6)
Brethine · Terbutaline Sulfate · Bricanyl
Score:
#2506 in Biology
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#3129 in Chemistry
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- Comparison of a 2-Agonist, Terbutaline, with an Inhaled Corticosteroid, Budesonide, in Newly Detected Asthma (The New England Journal of Medicine, 1991)
- A comparative study of the effects of an inhaled corticosteroid, budesonide, and a 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma : a randomized, double-blind, parallel-group controlled trial (The Journal of Allergy and Clinical Immunology, 1992)
- Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: A comparison between budesonide and terbutaline (The Journal of Allergy and Clinical Immunology, 1985)
- REBOUND INCREASE IN BRONCHIAL RESPONSIVENESS AFTER TREATMENT WITH INHALED TERBUTALINE (The Lancet, 1988)
- Inflammatory Cells and Eosinophilic Activity in Asthmatics Investigated by Bronchoalveolar Lavage: The Effects of Antiasthmatic Treatment with Budesonide or Terbutaline (The American review of respiratory disease, 1990)
- Use of cyclodextrins in capillary zone electrophoresis : Resolution of terbutaline and propranolol enantiomers (Journal of Chromatography A, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Brethine
- Terbutaline Sulfate
- Bricanyl
- Brethaire
- Butaliret
- Bricanyl SA
- Butalitab
- Contimit
- Terbul
- Terbasmin
- Monovent
- Taziken
- KWD 2019
- terbutalin von ct
- Terbuturmant
- Arubendol
- KWD2019
- Terbutalin AL
- Terbutalin ratiopharm
- KWD-2019
- Asthmoprotect
- Terbutalin-ratiopharm
- Tedipulmo
- Terbutalin Stada
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- Pubchem - terbutaline
- Wikipedia - terbutaline
Terbutaline (trade names "Bronclyn",Brethine, Bricanyl, Brethaire, or Terbulin) is a 2 adrenergic receptor agonist, used as a "reliever" inhaler in the management of asthma symptoms and as a tocolytic (anti-contraction medication) to delay preterm labor for up to 48 hours. This time can then be used to administer steroid injections to the mother which help fetal lung maturity and reduce complications of prematurity. It should not be used to prevent preterm labor or delay labor more than 4872 hours.
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Synthesis
Reactant
+
5-Chlororesorcinol
(Grignard alcohol)
Reactant
+
2-Chloro-2-methylpropane
(Alkylation of primary amines)
Reactant
+
tert-Butylamine
(Reductive amination)
resorcinol
+
Reactant
(Friedel-Crafts alkylation)
Tert-butylboronic Acid
+
Reactant
(Chan-Lam coupling reaction)
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