| Weight | 211.221 g/mol |
|---|---|
| Formula | C9H13N3O3 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
zalcitabine (7481-89-2)
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#3 in Virology
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#66 in Microbiology
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#905 in Biology
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- Treatment of Human Immunodeficiency Virus Infection with Saquinavir, Zidovudine, and Zalcitabine (The New England Journal of Medicine, 1996)
- Delta: A randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals (The Lancet, 1996)
- A Comparative Trial of Didanosine or Zalcitabine after Treatment with Zidovudine in Patients with Human Immunodeficiency Virus Infection (The New England Journal of Medicine, 1994)
- Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells. (Journal of the Neurological Sciences, 1997)
- Zidovudine alone or in combination with didanosine or zalcitabine in HIV-infected patients with the acquired immunodeficiency syndrome or fewer than 200 CD4 cells per cubic millimeter (The New England Journal of Medicine, 1996)
- Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine (Hepatology, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H341: Suspected of causing genetic defects
Warning Germ cell mutagenicity - Category 2 - H361: Suspected of damaging fertility or the unborn child
Warning Reproductive toxicity - Category 2 - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 -
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- Pubchem - zalcitabine
- Wikipedia - zalcitabine
Zalcitabine (2-3-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen.
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zalcitabine
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