| Weight | 316.485 g/mol |
|---|---|
| Formula | C21H32O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
5a-Pregnane-3,20-dione (566-65-4)
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- Sigma-Aldrich - 5a-Pregnane-3,20-dione120.50 - 217.50 USD
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SMILESCC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C
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InChIKeyXMRPGKVKISIQBV-UHFFFAOYSA-N
- Pubchem - 5a-Pregnane-3,20-dione
- Wikipedia - 5-Dihydroprogesterone
5-Dihydroprogesterone (5-DHP), also known as allopregnanedione, as well as 5-pregnane-3,20-dione, is an endogenous progestogen and neurosteroid that is synthesized from progesterone. It is also an intermediate in the synthesis of allopregnanolone and isopregnanolone from progesterone. 5-DHP is an agonist of the progesterone receptor and a positive allosteric modulator of the GABAA receptor (albeit with an affinity for this receptor that is regarded as relatively low (in comparison to 3-hydroxylated progesterone metabolites such as allopregnanolone and pregnanolone)).
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5a-Pregnane-3,20-dione
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