| Weight | 350.455 g/mol |
|---|---|
| Formula | C20H30O5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
Andrographolide (5508-58-7)
isoandrographolide · 17-hydro-9-dehydro-andrographolide
Score:
#1722 in Biochemistry
,
#3816 in Biology
,
#4803 in Chemistry
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- Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect. (British Journal of Pharmacology, 2002)
- A phase I trial of andrographolide in HIV positive patients and normal volunteers. (Phytotherapy Research, 2000)
- Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50. (Journal of Immunology, 2004)
- Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata (Journal of Experimental Therapeutics and Oncology, 2003)
- Hepatoprotective activity of andrographolide from Andrographis paniculata against carbontetrachloride. (Indian Journal of Medical Research, 1990)
- A Novel Antiinflammatory Role for Andrographolide in Asthma via Inhibition of the Nuclear Factor-B Pathway (American Journal of Respiratory and Critical Care Medicine, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - isoandrographolide
- 17-hydro-9-dehydro-andrographolide
-
SMILESCC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O
-
InChIKeyBOJKULTULYSRAS-UHFFFAOYSA-N
- Pubchem - Andrographolide
- Wikipedia - Andrographolide
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke.
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Andrographolide
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