| Weight | 505.571 g/mol |
|---|---|
| Formula | C28H31N3O6 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Benidipine (105979-17-7)
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- Benidipine stimulates nitric oxide synthase and improves coronary circulation in hypertensive rats. (American Journal of Hypertension, 1999)
- A Ca channel blocker, benidipine, increases coronary blood flow and attenuates the severity of myocardial ischemia via no-dependent mechanisms in dogs (Journal of the American College of Cardiology, 1999)
- Benidipine Improves Endothelial Function in Renal Resistance Arteries of Hypertensive Rats (Hypertension, 1996)
- Long-acting calcium channel blocker benidipine suppresses expression of angiogenic growth factors and prevents cardiac remodelling in a Type II diabetic rat model (Diabetologia, 2002)
- Benidipine, a dihydropyridine-calcium channel blocker, prevents lysophosphatidylcholine-induced injury and reactive oxygen species production in human aortic endothelial cells. (Atherosclerosis, 2005)
- Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells. (British Journal of Pharmacology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C(C(=C(N1)C)C(=O)OC2CCCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC
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- Pubchem - Benidipine
- Wikipedia - benidipine
Benidipine (INN), also known as Benidipinum or benidipine hydrochloride, is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). It is a triple L-, T-, and N-type calcium channel blocker. It is reno- and cardioprotective.
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