| Weight | 424.544 g/mol |
|---|---|
| Formula | C28H28N2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
Difenoxin (28782-42-5, 35607-36-4)
diphenoxylic acid · difenoxin hydrochloride · difenoxin hydrochloride, 14C-labeled
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- Difenoxin and loperamide: studies on possible mechanisms of intestinal antisecretory action. (Naunyn-schmiedebergs Archives of Pharmacology, 1993)
- The measurement of diphenoxylic acid in plasma following administration of diphenoxylate (Journal of Mass Spectrometry, 1976)
- The evaluation and application of a radioimmunoassay for the measurement of diphenoxylic acid, the major metabolite of diphenoxylate hydrochloride (Lomotil), in human plasma. (Journal of Pharmacological Methods, 1987)
- Difenoxin hydrochloride polymorphism (International Journal of Pharmaceutics, 1979)
- A gas-liquid chromatographic method for the analysis of diphenoxylic acid in urine (Chromatographia, 1976)
- [Difenoxin hydrochloride; a new antidiarrheal agent; preliminary results of cases of chronic diarrhoea (author's transl)]. (Praxis Journal of Philosophy, 1976)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - diphenoxylic acid
- difenoxin hydrochloride
- difenoxin hydrochloride, 14C-labeled
-
SMILESC1CN(CCC1(C2=CC=CC=C2)C(=O)O)CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4
-
InChIKeyUFIVBRCCIRTJTN-UHFFFAOYSA-N
- Pubchem - Difenoxin
- Wikipedia - difenoxin hydrochloride
Difenoxin (Motofen, R-15403) is an opioid drug used, often in combination with atropine, to treat diarrhea. It is the principal metabolite of diphenoxylate. Difenoxin crosses the blood brain barrier and induces some euphoria; it is often sold with or administered with atropine to reduce the potential for abuse and overdose.
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