| Weight | 382.529 g/mol |
|---|---|
| Formula | C22H26N2O2S |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Eletriptan (177834-92-3, 143322-58-1)
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- Eletriptan in acute migraine: A double-blind, placebo-controlled comparison to sumatriptan (Neurology, 2000)
- Eletriptan in acute migraine: a double-blind, placebo-controlled comparison to sumatriptan. Eletriptan Steering Committee. (Neurology, 2000)
- Eletriptan in the early treatment of acute migraine : influence of pain intensity and time of dosing (Cephalalgia, 2005)
- Efficacy, Tolerability and Safety of Oral Eletriptan and Ergotamine plus Caffeine (Cafergot) in the Acute Treatment of Migraine: A Multicentre, Randomised, Double-Blind, Placebo-Controlled Comparison (European Neurology, 2002)
- No effect of eletriptan administration during the aura phase of migraine (European Journal of Neurology, 2004)
- Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels (Neurology, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1CCCC1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
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InChIKeyPWVXXGRKLHYWKM-UHFFFAOYSA-N
- Pubchem - Eletriptan
- Wikipedia - eletriptan
Eletriptan (trade name Relpax, used in the form of eletriptan hydrobromide) is a second generation triptan drug intended for treatment of migraine headaches. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan is marketed and manufactured by Pfizer Inc.
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Synthesis
Reactant
+
(S)-2-Chloromethyl-1-methyl-pyrrolidine
(Friedel-Crafts alkylation)
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