| Weight | 295.379 g/mol | 
|---|---|
| Formula | C16H25NO4 | 
| Hydrogen Acceptors | 5 | 
| Hydrogen Donors | 2 | 
| Aromatic Rings | 1 | 
| Rotatable Bonds | 9 | 
ESMOLOL (81147-92-4, 103598-03-4)
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 LabBot
      - Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock A Randomized Clinical Trial (JAMA, 2013)
 - Esmolol versus verapamil in the acute treatment of atrial fibrillation or atrial flutter (American Journal of Cardiology, 1989)
 - Comparison of sodium nitroprusside- and esmolol-induced controlled hypotension for functional endoscopic sinus surgery (Canadian Journal of Anaesthesia-journal Canadien D Anesthesie, 1995)
 - Kinetics of esmolol, an ultra-short-acting beta blocker, and of its major metabolite (Clinical Pharmacology & Therapeutics, 1983)
 - The use of esmolol as an alternative to remifentanil during desflurane anesthesia for fast-track outpatient gynecologic laparoscopic surgery. (Anesthesia & Analgesia, 2001)
 - WHICH DRUG PREVENTS TACHYCARDIA AND HYPERTENSION ASSOCIATED WITH TRACHEAL INTUBATION : LIDOCAINE, FENTANYL, OR ESMOLOL ? (Anesthesia & Analgesia, 1991)
 - 
            
            Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 
          SMILESCC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O
 - 
          InChIKeyAQNDDEOPVVGCPG-UHFFFAOYSA-N
 - Pubchem - ESMOLOL
 - Wikipedia - esmolol
          
          Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. It is a class II antiarrhythmic. Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in the heart and other organs of the body.
 
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Synthesis
                
                ISOPROPYLAMINE 
                
                
                 + 
                
                Reactant
                
                (Alkylation of primary amines)
                
              
              
        
            
                
                Methyl 3-(4-hydroxyphenyl)propionate 
                
                
                 + 
                
                Reactant
                
                (Williamson ether)
                
              
              
        
            
                
                Reactant
                
                
                 + 
                
                CID 5475562 
                
                (Chan-Lam coupling reaction)
                
              
              
        
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 ESMOLOL 
                  