Weight | 295.379 g/mol |
---|---|
Formula | C16H25NO4 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 9 |
ESMOLOL (81147-92-4, 103598-03-4)
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- Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock A Randomized Clinical Trial (JAMA, 2013)
- Esmolol versus verapamil in the acute treatment of atrial fibrillation or atrial flutter (American Journal of Cardiology, 1989)
- Comparison of sodium nitroprusside- and esmolol-induced controlled hypotension for functional endoscopic sinus surgery (Canadian Journal of Anaesthesia-journal Canadien D Anesthesie, 1995)
- Kinetics of esmolol, an ultra-short-acting beta blocker, and of its major metabolite (Clinical Pharmacology & Therapeutics, 1983)
- The use of esmolol as an alternative to remifentanil during desflurane anesthesia for fast-track outpatient gynecologic laparoscopic surgery. (Anesthesia & Analgesia, 2001)
- WHICH DRUG PREVENTS TACHYCARDIA AND HYPERTENSION ASSOCIATED WITH TRACHEAL INTUBATION : LIDOCAINE, FENTANYL, OR ESMOLOL ? (Anesthesia & Analgesia, 1991)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O
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InChIKeyAQNDDEOPVVGCPG-UHFFFAOYSA-N
- Pubchem - ESMOLOL
- Wikipedia - esmolol
Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. It is a class II antiarrhythmic. Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in the heart and other organs of the body.
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Synthesis
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
Methyl 3-(4-hydroxyphenyl)propionate
+
Reactant
(Williamson ether)
Reactant
+
CID 5475562
(Chan-Lam coupling reaction)
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