| Weight | 267.369 g/mol |
|---|---|
| Formula | C15H25NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 9 |
metoprolol (51384-51-1, 37350-58-6)
Lopressor · Metoprolol Tartrate · Toprol
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#1087 in Chemistry
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- Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) (The Lancet, 1999)
- Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. (The Lancet, 2003)
- Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): A randomised controlled trial (The Lancet, 2008)
- Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy (The Lancet, 1993)
- Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure : The metoprolol CR/XL randomized intervention trial in congestive heart failure (MERIT-HF) (JAMA, 2000)
- EFFECT ON MORTALITY OF METOPROLOL IN ACUTE MYOCARDIAL INFARCTION: A Double-blind Randomised Trial (The Lancet, 1981)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lopressor
- Metoprolol Tartrate
- Toprol
- Toprol XL
- metoprolol succinate
- Betaloc
- Succinate, Metoprolol
- Betalok
- Beloc Duriles
- H 9326
- Spesicor
- H 93-26
- Betaloc Astra
- Seloken
- CGP2175
- BetalocAstra
- metoprolol CR-XL
- H 93 26
- CGP-2175
- CR-XL, Metoprolol
- Toprol-XL
- CGP 2175
- Betaloc-Astra
- Spesikor
- Beloc-Duriles
- Metoprolol CR XL
- BelocDuriles
- ToprolXL
-
SMILESCC(C)NCC(COC1=CC=C(C=C1)CCOC)O
-
InChIKeyIUBSYMUCCVWXPE-UHFFFAOYSA-N
- Pubchem - metoprolol
- Wikipedia - metoprolol
Metoprolol, marketed under the tradename Lopressor among others, is a medication of the selective 1 receptor blocker type. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines.
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Synthesis
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
4-(2-Methoxyethyl)phenol
+
Reactant
(Williamson ether)
Reactant
+
CID 5475562
(Chan-Lam coupling reaction)
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