| Weight | 612.632 g/mol |
|---|---|
| Formula | C31H36N2O11 |
| Hydrogen Acceptors | 11 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 8 |
novobiocin (303-81-1, 1476-53-5)
Novobiocin Sodium · Streptonivicin · Monosodium Salt Novobiocin
Score:
#198 in Microbiology
,
#729 in Biochemistry
,
#2014 in Biology
,
#2461 in Chemistry
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- Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase (Proceedings of the National Academy of Sciences of the United States of America, 1976)
- The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. (Journal of Biological Chemistry, 2000)
- Novobiocin and Related Coumarins and Depletion of Heat Shock Protein 90-Dependent Signaling Proteins (Journal of the National Cancer Institute, 2000)
- Energy coupling in DNA gyrase and the mechanism of action of novobiocin (Proceedings of the National Academy of Sciences of the United States of America, 1978)
- Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. (Current Medicinal Chemistry, 2008)
- The BaeSR Two-Component Regulatory System Activates Transcription of the yegMNOB (mdtABCD) Transporter Gene Cluster in Escherichia coli and Increases Its Resistance to Novobiocin and Deoxycholate (Journal of Bacteriology, 2002)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Novobiocin Sodium
- Streptonivicin
- Monosodium Salt Novobiocin
- Crystallinic Acid
- Novobiocin Calcium
-
SMILESCC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O
-
InChIKeyYJQPYGGHQPGBLI-UHFFFAOYSA-N
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