Weight | 357.45 g/mol |
---|---|
Formula | C21H27NO4 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 6 |
NSC 35045 (2688-77-9)
laudanosine
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - laudanosine
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SMILESCN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC
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InChIKeyKGPAYJZAMGEDIQ-UHFFFAOYSA-N
- Pubchem - NSC 35045
- Wikipedia - laudanosine
Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium. Laudanosine also occurs naturally in minute amounts (0.1%) in opium, from which it was first isolated in 1871.
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