| Weight | 1019.261 g/mol |
|---|---|
| Formula | C49H66N10O10S2 |
| Hydrogen Acceptors | 14 |
| Hydrogen Donors | 13 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 17 |
Octreotide (83150-76-9)
Score:
#571 in Neuroscience
,
#2572 in Biology
,
#3206 in Chemistry
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- Somatostatin receptor scintigraphy with [111In-DTPA-d-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients (European Journal of Nuclear Medicine and Molecular Imaging, 1993)
- Placebo-Controlled, Double-Blind, Prospective, Randomized Study on the Effect of Octreotide LAR in the Control of Tumor Growth in Patients With Metastatic Neuroendocrine Midgut Tumors: A Report From the PROMID Study Group (Journal of Clinical Oncology, 2009)
- 68Ga-DOTA-Tyr3-Octreotide PET in Neuroendocrine Tumors: Comparison with Somatostatin Receptor Scintigraphy and CT (The Journal of Nuclear Medicine, 2007)
- Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study (The Lancet, 2011)
- Efficacy of RAD001 (Everolimus) and Octreotide LAR in Advanced Low- to Intermediate-Grade Neuroendocrine Tumors: Results of a Phase II Study (Journal of Clinical Oncology, 2008)
- Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide (Hepatology, 1999)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O
-
InChIKeyDEQANNDTNATYII-UHFFFAOYSA-N
- Pubchem - Octreotide
- Wikipedia - Octreotide
Octreotide (trade name Sandostatin, among others) is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was first synthesized in 1979 by the chemist Wilfried Bauer.
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Octreotide
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