Weight | 720.962 g/mol |
---|---|
Formula | C37H48N6O5S2 |
Hydrogen Acceptors | 9 |
Hydrogen Donors | 4 |
Aromatic Rings | 4 |
Rotatable Bonds | 17 |
ritonavir (155213-67-5)
Score:
#43 in Microbiology
,
#622 in Biology
,
#663 in Chemistry
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- Ordered accumulation of mutations in HIV protease confers resistance to ritonavir (Nature Medicine, 1996)
- LopinavirRitonavir versus Nelfinavir for the Initial Treatment of HIV Infection (The New England Journal of Medicine, 2002)
- A SHORT-TERM STUDY OF THE SAFETY, PHARMACOKINETICS, AND EFFICACY OF RITONAVIR, AN INHIBITOR OF HIV-1 PROTEASE (The New England Journal of Medicine, 1995)
- Ritonavir: An Extraordinary Example of Conformational Polymorphism (Pharmaceutical Research, 2001)
- Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease (The Lancet, 1998)
- A Preliminary Study of Ritonavir, an Inhibitor of HIV-1 Protease, to Treat HIV-1 Infection (The New England Journal of Medicine, 1995)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
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InChIKeyNCDNCNXCDXHOMX-UHFFFAOYSA-N
- Pubchem - ritonavir
- Wikipedia - ritonavir
Ritonavir, sold under the trade name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy (HAART). Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.
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