| Weight | 575.687 g/mol |
|---|---|
| Formula | C31H33N3O6S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 8 |
zafirlukast (107753-78-6)
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- Pulmonary Infiltrates, Eosinophilia, and Cardiomyopathy Following Corticosteroid Withdrawal in Patients With Asthma Receiving Zafirlukast (JAMA, 1998)
- Variant LTC 4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast (Thorax, 2000)
- Effectiveness of the Leukotriene Receptor Antagonist Zafirlukast for Mild-to-Moderate Asthma: A Randomized, Double-Blind, Placebo-Controlled Trial (Annals of Internal Medicine, 1997)
- Effect of zafirlukast (accolate) on cellular mediators of inflammation: Bronchoalveolar lavage fluid findings after segmental antigen challenge (American Journal of Respiratory and Critical Care Medicine, 1998)
- Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids. (American Journal of Respiratory and Critical Care Medicine, 2000)
- Zafirlukast for symptomatic mild-to-moderate asthma : A 13-week multicenter study (Clinical Therapeutics, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
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- Pubchem - zafirlukast
- Wikipedia - zafirlukast
Zafirlukast is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma. While zafirlukast is generally well-tolerated, headache and stomach upset often occur. Some rare side effects can occur, which can be life-threatening, such as liver failure.
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