| Weight | 267.328 g/mol |
|---|---|
| Formula | C17H17NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
apomorphine
Apomorphine Hydrochloride · Apomorphin Teclapharm · Hemihydrate Apomorphine Hydrochloride
58-00-4, 314-19-2, 41372-20-7
Score:
#44 in Neurology
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#234 in Neuroscience
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#1081 in Biology
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- Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum (Brain Research, 1975)
- Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats (Psychopharmacology, 1967)
- Evidence for dopamine receptor stimulation by apomorphine (Journal of Pharmacy and Pharmacology, 1967)
- Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines (Neuropharmacology, 1974)
- Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine (Annals of Neurology, 1992)
- Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. (Psychopharmacology, 1995)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Apomorphine Hydrochloride
- Apomorphin Teclapharm
- Hemihydrate Apomorphine Hydrochloride
- Apomorphin-Teclapharm
- Teclapharm Brand of Apomorphine Hydrochloride
- Aguettant Brand of Apomorphine Hydrochloride
- Britaject
- Apomorphine Hydrochloride Anhydrous
- ApomorphinTeclapharm
- Apokinon
- Britannia Brand of Apomorphine Hydrochloride
- Anhydrous Apomorphine Hydrochloride
- Apomorphine Chloride
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SMILESCN1CCC2=CC=CC3=C2C1CC4=C3C(=C(C=C4)O)O
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InChIKeyVMWNQDUVQKEIOC-UHFFFAOYSA-N
- Pubchem - apomorphine
- Wikipedia - apomorphine
Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors. It also acts as an antagonist of 5-HT2 and -adrenergic receptors with high affinity. The compound is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix.
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