| Weight | 325.449 g/mol |
|---|---|
| Formula | C18H31NO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 12 |
BISOPROLOL (66722-44-9)
Concor · Bisoprolol Fumarate · EMD-33512
Score:
#1074 in Biology
,
#1204 in Chemistry
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- The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial (The Lancet, 1999)
- The Effect of Bisoprolol on Perioperative Mortality and Myocardial Infarction in High-Risk Patients Undergoing Vascular Surgery (The New England Journal of Medicine, 1999)
- A randomized trial of beta-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). CIBIS Investigators and Committees. (Circulation, 1994)
- Heart Rate and Cardiac Rhythm Relationships With Bisoprolol Benefit in Chronic Heart Failure in CIBIS II Trial (Circulation, 2001)
- Effect on Survival and Hospitalization of Initiating Treatment for Chronic Heart Failure With Bisoprolol Followed by Enalapril, as Compared With the Opposite Sequence. Results of the Randomized Cardiac Insufficiency Bisoprolol Study (CIBIS) III. (Circulation, 2005)
- Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial (The Lancet, 2015)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Concor
- Bisoprolol Fumarate
- EMD-33512
- Bisoprolol Fumarate (1:1) Salt, (+-)-Isomer
- Bisoprolol Hydrochloride
- Bisoprolol, (-)-Isomer
- CL-297939
- CL 297939
- Bisoprolol, Fumarate (1:1) Salt
- Bisoprolol Fumarate (2:1) Salt, (+-)-Isomer
- Bisoprolol, Fumarate (2:1) Salt
- Bisoprolol, (+-)-Isomer
- CL297939
- EMD33512
- Bisoprolol Methanesulfonate Salt
- EMD 33512
-
SMILESCC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O
-
InChIKeyVHYCDWMUTMEGQY-UHFFFAOYSA-N
- Pubchem - BISOPROLOL
- Wikipedia - bisoprolol
Bisoprolol, marketed under the tradename Zebeta among others, is a medication most commonly used for heart diseases. This specifically includes high blood pressure, chest pain from not enough blood flow to the heart, and heart failure. It is taken by mouth.
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Synthesis
2-(Propan-2-ylamino)acetaldehyde
+
Reactant
(Grignard alcohol)
Reactant
+
ISOPROPYLAMINE
(Reductive amination)
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BISOPROLOL
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