| Weight | 547.59 g/mol |
|---|---|
| Formula | C24H29N5O8S |
| Hydrogen Acceptors | 11 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
Doxazosin mesylate (77883-43-3)
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- Sigma-Aldrich - Doxazosin mesylate108.50 - 418.50 USD
- Fisher Scientific - Search for Doxazosin mesylate
- TCI - Doxazosin mesylate50.00 - 190.00 USD
- Practical chemical and enzymatic technologies for (S)-1,4-benzodioxan-2-carboxypiperizine intermediate in the synthesis of (S)-doxazosin mesylate (Tetrahedron-asymmetry, 2001)
- Enantiomeric resolution of doxazosin mesylate and its process-related substances on polysaccharide chiral stationary phases. (Journal of Pharmaceutical and Biomedical Analysis, 2006)
- Flow injection analysis of doxazosin mesylate using UV-detection. (Journal of Pharmaceutical and Biomedical Analysis, 2002)
- Matrix tablets based on carrageenans with dual controlled release of doxazosin mesylate. (International Journal of Pharmaceutics, 2010)
- In vitro vs. canine data for assessing early exposure of doxazosin base and its mesylate salt (European Journal of Pharmaceutics and Biopharmaceutics, 2012)
- Polymorphism of doxazosin mesylate (Archives of Pharmacal Research, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCOC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O
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- Pubchem - Doxazosin mesylate
- Wikipedia - doxazosin mesylate
Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an 1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH). In March 2000, the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) study stopped its arm of the trial looking at alpha blockers, because doxazosin was less effective than a simple diuretic, and because patients on doxazosin had a 25% higher rate of cardiovascular disease and twice the rate of congestive heart failure as patients on diuretics. Pfizer, aware of the results before publication, launched a marketing campaign in early 2000, and sales were largely unaffected, despite the dangers highlighted by the study.
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Doxazosin mesylate
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