| Weight | 501.667 g/mol |
|---|---|
| Formula | C32H39NO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 10 |
fexofenadine (83799-24-0)
Allegra · fexofenadine hydrochloride · Aventis brand of fexofenadine hydrochloride
Score:
#429 in Biochemistry
,
#579 in Physics
,
#1432 in Biology
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#1677 in Chemistry
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- OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine (Drug Metabolism and Disposition, 1999)
- Fruit juices inhibit organic anion transporting polypeptidemediated drug uptake to decrease the oral availability of fexofenadine (Clinical Pharmacology & Therapeutics, 2002)
- MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine (British Journal of Clinical Pharmacology, 2002)
- Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator. (Annals of Internal Medicine, 2000)
- Effect of St John's wort on the pharmacokinetics of fexofenadine. (Clinical Pharmacology & Therapeutics, 2002)
- The effect of rifampin administration on the disposition of fexofenadine (Clinical Pharmacology & Therapeutics, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Allegra
- fexofenadine hydrochloride
- Aventis brand of fexofenadine hydrochloride
- MDL-16455
- MDL 16.455
- Telfast
- Aventis Behring brand of fexofenadine hydrochloride
- alpha-(4-(1-carboxy-1-methylethyl)phenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol
- MDL 16455
- MDL 16,455A
- Hoechst brand of fexofenadine hydrochloride
- Aventis Pharma brand of fexofenadine hydrochloride
-
SMILESCC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O
-
InChIKeyRWTNPBWLLIMQHL-UHFFFAOYSA-N
- Pubchem - fexofenadine
- Wikipedia - fexofenadine
Fexofenadine, sold under the trade name Allegra among others is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Therapeutically, fexofenadine is a selective peripheral H1-blocker. Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines.
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