| Weight | 287.359 g/mol |
|---|---|
| Formula | C17H21NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
galanthamine (23173-12-8, 357-70-0)
Score:
#268 in Neuroscience
,
#333 in Biochemistry
,
#1233 in Biology
,
#1418 in Chemistry
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- Galanthamine from snowdropthe development of a modern drug against Alzheimers disease from local Caucasian knowledge (Journal of Ethnopharmacology, 2004)
- Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine. (Journal of Pharmacology and Experimental Therapeutics, 1996)
- Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution. (FEBS Letters, 1999)
- Use of Biomimetic Diversity-Oriented Synthesis to Discover Galanthamine-Like Molecules with Biological Properties beyond Those of the Natural Product (Journal of the American Chemical Society, 2001)
- Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo (Life Sciences, 1990)
- Divergent enantioselective synthesis of (-)-galanthamine and (-)-morphine. (Journal of the American Chemical Society, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O
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InChIKeyASUTZQLVASHGKV-UHFFFAOYSA-N
- Pubchem - galanthamine
- Wikipedia - galantamine
Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of cognitive decline in mild to moderate Alzheimer's disease and various other memory impairments. It is an alkaloid that has been isolated from the bulbs and flowers of Galanthus caucasicus (Caucasian snowdrop), Galanthus woronowii (Voronov's snowdrop), and some other members of the family Amaryllidaceae, such as Narcissus (daffodil), Leucojum aestivum (snowflake), and Lycoris including Lycoris radiata (red spider lily). It can also be produced synthetically.
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