| Weight | 500.432 g/mol |
|---|---|
| Formula | C26H30Cl2F3NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 10 |
Halofantrine (69756-53-2)
Halfan · WR-171,669 · halofantrine hydrochloride
Score:
#350 in Microbiology
,
#1113 in Biochemistry
,
#2844 in Biology
,
#3562 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for Halofantrine
- Fisher Scientific - Search for Halofantrine
- TCI - Search for Halofantrine
- Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine (International Journal of Pharmaceutics, 1998)
- Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. (Proceedings of the National Academy of Sciences of the United States of America, 1994)
- Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin (The Journal of Infectious Diseases, 2006)
- Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand (Molecular and Biochemical Parasitology, 1993)
- Cardiac effects of antimalarial treatment with halofantrine (The Lancet, 1993)
- Effect of Short, Medium, and LongChain Fatty AcidBased Vehicles on the Absolute Oral Bioavailability and Intestinal Lymphatic Transport of Halofantrine and Assessment of Mass Balance in LymphCannulated and Noncannulated Rats (Journal of Pharmaceutical Sciences, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Halfan
- WR-171,669
- halofantrine hydrochloride
- WR 171669
- WR 171,699
- WR-171699
- 1-(1,3-dichloro-6-trifluoromethyl-9-phenanthryl)-3-di(n-butyl)aminopropanol HCl
-
SMILESCCCCN(CCCC)CCC(C1=C2C=CC(=CC2=C3C=C(C=C(C3=C1)Cl)Cl)C(F)(F)F)O
-
InChIKeyFOHHNHSLJDZUGQ-UHFFFAOYSA-N
- Pubchem - Halofantrine
- Wikipedia - Halofantrine
Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Similar Compounds
Mefloquine hydrochloride
(51742-86-0, 51773-92-3)
8 alternate names
3 suppliers
Hydroxyzine dihydrochloride
(2192-20-3)
8 alternate names
3 suppliers
Quinacrine hydrochloride
(130-42-7, 69-05-6)
8 alternate names
3 suppliers
QUINACRINE DIHYDROCHLORIDE
(69-05-6)
8 alternate names
3 suppliers
CHLORCYCLIZINE HYDROCHLORIDE
(1620-21-9, 14362-31-3)
8 alternate names
3 suppliers
HYDROXYCHLOROQUINE SULFATE
(747-36-4)
8 alternate names
3 suppliers
Acridine mustard
(146-59-8)
8 alternate names
3 suppliers
lonidamine
(50264-69-2)
8 alternate names
3 suppliers
FLUOXETINE HYDROCHLORIDE
(56296-78-7, 59333-67-4)
8 alternate names
3 suppliers
Cinacalcet hydrochloride
(364782-34-3)
8 alternate names
3 suppliers
Quinacrine dihydrochloride dihydrate
(6151-30-0, 69-05-6)
8 alternate names
3 suppliers
FLUAZIFOP-BUTYL
(86334-14-7, 69806-50-4)
8 alternate names
3 safety hazards
3 suppliers
Bisphenol AF
(1478-61-1)
8 alternate names
3 suppliers
Hydroxyzine hydrochloride
(14729-22-7, 1244-76-4)
8 alternate names
3 suppliers
PHENIRAMINE MALEATE
(132-20-7)
8 alternate names
3 suppliers
Araten phosphate
(1446-17-9)
8 alternate names
3 suppliers
Diflufenican
(83164-33-4)
8 alternate names
1 safety hazard
3 suppliers
Chlorpromazine hydrochloride
(69-09-0)
8 alternate names
3 suppliers
Chloroquine diphosphate
(50-63-5)
8 alternate names
3 suppliers
Trifluoperazine dihydrochloride
(440-17-5)
8 alternate names
3 suppliers
Acequinocyl
(57960-19-7)
8 alternate names
3 safety hazards
3 suppliers
BIFENOX
(42576-02-3)
8 alternate names
3 suppliers
96-69-5
(96-69-5, 57062-46-1)
8 alternate names
1 safety hazard
3 suppliers
VITAMIN A PALMITATE
(79-81-2)
8 alternate names
3 suppliers
Cerebrosterol
(474-73-7)
8 alternate names
3 suppliers
FLUTOLANIL
(66332-96-5)
8 alternate names
1 safety hazard
3 suppliers
Cyclizine 2HCl
(303-25-3, 5897-18-7)
8 alternate names
3 suppliers
pridinol
(511-45-5)
8 alternate names
3 suppliers
Loxapine succinate
(27833-64-3)
8 alternate names
3 suppliers
6398-98-7
(6398-98-7, 69-44-3)
8 alternate names
3 suppliers
22R-hydroxycholesterol
(22348-64-7, 17954-98-2)
8 alternate names
3 suppliers
CYHALOTHRIN
(68085-85-8, 91465-08-6)
8 alternate names
4 safety hazards
3 suppliers
Clomipramine hydrochloride
(17321-77-6)
8 alternate names
3 suppliers
Cetirizine dihydrochloride
(83881-52-1)
8 alternate names
3 suppliers
PROPICONAZOLE
(60207-90-1)
8 alternate names
4 safety hazards
3 suppliers
141-22-0
(141-22-0)
8 alternate names
3 suppliers
L-Ascorbyl 6-palmitate
(137-66-6)
8 alternate names
3 suppliers
Halofantrine
CAS Directory
