| Weight | 473.446 g/mol |
|---|---|
| Formula | C20H23N7O7 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 7 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 10 |
leucovorin (58-05-9, 1492-18-8)
Folinic Acid · Citrovorum Factor · Calcium Leucovorin
Score:
#366 in Biochemistry
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#1311 in Biology
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#1524 in Chemistry
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- Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer (The New England Journal of Medicine, 2004)
- Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer (Journal of Clinical Oncology, 2000)
- Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer (The New England Journal of Medicine, 2000)
- Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer (The New England Journal of Medicine, 2004)
- A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal Cancer (Journal of Clinical Oncology, 2004)
- Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200 (Journal of Clinical Oncology, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Folinic Acid
- Citrovorum Factor
- Calcium Leucovorin
- Wellcovorin
- Leukovorin
- Calcium Folinate
- Folinic Acid SF
- Leucovorin, Calcium (1:1) Salt, (DL)-Isomer
- Leucovorin, (DL)-Isomer
- Monosodium Salt Leucovorin
- Leucovorin, (R)-Isomer
- 5-Formyltetrahydrofolate
- Leukovorum
- Leucovorin, (D)-Isomer
- 5 Formyltetrahydropteroylglutamate
- 5-Formyltetrahydropteroylglutamate
- Leucovorin, Calcium (1:1) Salt, Pentahydrate
- Folinic Acid-SF
- 5 Formyltetrahydrofolate
- N(5)-Formyltetrahydrofolate
- Leucovorin, Calcium (1:1) Salt
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SMILESC1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
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InChIKeyVVIAGPKUTFNRDU-UHFFFAOYSA-N
- Pubchem - leucovorin
- Wikipedia - Sodium folinate
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. It is also used in combination with 5-fluorouracil to treat colorectal cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning. It is taken by mouth, injection into a muscle, or injection into a vein.
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