| Weight | 277.368 g/mol |
|---|---|
| Formula | C15H23N3O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
N-Acetylprocainamide (32795-44-1)
Acetylprocainamide · Acecainide Monohydrochloride · Acecainide
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- Antiarrhythmic efficacy, pharmacokinetics and safety of N-acetylprocainamide in human subjects: comparison with procainamide. (American Journal of Cardiology, 1980)
- Antiarrhythmic potency of N-acetylprocainamide (Clinical Pharmacology & Therapeutics, 1975)
- Absolute bioavailability in man of N-acetylprocainamide determined by a novel stable isotope method. (Clinical Pharmacology & Therapeutics, 1975)
- Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function. (Clinical Pharmacology & Therapeutics, 1977)
- N-acetylprocainamide: an active metabolite of procainamide. (Experimental Biology and Medicine, 1974)
- Antibodies to Nuclear Antigens in Patients Treated with Procainamide or Acetylprocainamide (The New England Journal of Medicine, 1979)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Acetylprocainamide
- Acecainide Monohydrochloride
- Acecainide
- N Acetylprocainamide
- Acecainide Hydrochloride
-
SMILESCCN(CC)CCNC(=O)C1=CC=C(C=C1)NC(=O)C
-
InChIKeyKEECCEWTUVWFCV-UHFFFAOYSA-N
- Pubchem - N-Acetylprocainamide
- Wikipedia - acecainide
Acecainide (N-acetylprocainamide, NAPA) is an antiarrhythmic drug. Chemically, it is the N-acetylated metabolite of procainamide. It is a Class III antiarrhythmic agent, whereas procainamide is a Class Ia antiarrhythmic drug.
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Synthesis
Reactant
+
N,N-Diethylethylenediamine
(Schotten-Baumann amide from acid)
4-acetamidobenzamide
+
Reactant
(Amide N-alkylation)
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N-Acetylprocainamide
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