| Weight | 383.408 g/mol |
|---|---|
| Formula | C19H21N5O4 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
prazosin (19216-56-9)
Minipress · Prazosin Hydrochloride · Prazosin HCL
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#282 in Neuroscience
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#1501 in Chemistry
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- Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding. (Molecular Pharmacology, 1986)
- Binding characteristics of 3H-prazosin to rat brain -adrenergic receptors (European Journal of Pharmacology, 1979)
- Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin : A placebo-controlled study (American Journal of Psychiatry, 2003)
- A Parallel Group Placebo Controlled Study of Prazosin for Trauma Nightmares and Sleep Disturbance in Combat Veterans with Post-Traumatic Stress Disorder (Biological Psychiatry, 2007)
- EFFECT OF PROPRANOLOL AND PRAZOSIN ON BLOOD LIPIDS:The Oslo Study (The Lancet, 1980)
- Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension (Diabetologia, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Minipress
- Prazosin Hydrochloride
- Prazosin HCL
- Pfizer Brand of Prazosin Hydrochloride
- Furazosin
- Douglas Brand of Prazosin Hydrochloride
- Pratsiol
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SMILESCOC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC
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InChIKeyIENZQIKPVFGBNW-UHFFFAOYSA-N
- Pubchem - prazosin
- Wikipedia - prazosin
Prazosin, trade names Minipress, Vasoflex, Lentopres and Hypovase, is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD). It is an 1-blocker which acts as an inverse agonist at alpha-1 adrenergic receptors. These receptors are found on vascular smooth muscle, where they are responsible for the vasoconstrictive action of norepinephrine.
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