| Weight | 645.68 g/mol |
|---|---|
| Formula | C25H27N9O8S2 |
| Hydrogen Acceptors | 13 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
cefoperazone (62893-19-0)
Cefobid · Cefoperazone Sodium · T 1551
Score:
#251 in Microbiology
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#2309 in Biology
,
#2855 in Chemistry
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- TCI - cefoperazone99.00 - 332.00 USD
- Beta-lactam antibiotic therapy in febrile granulocytopenic patients: A randomized trial comparing cefoperazone plus piperacillin, ceftazidime plus piperacillin, and imipenem alone (Annals of Internal Medicine, 1991)
- Pharmacokinetics and Bacteriologic Efficacy of Moxalactam, Cefotaxime, Cefoperazone, and Rocephin in Experimental Bacterial Meningitis (The Journal of Infectious Diseases, 1981)
- Treatment of Typhoid Fever and Other Systemic Salmonelloses with Cefotaxime, Ceftriaxone, Cefoperazone, and Other Newer Cephalosporins (Clinical Infectious Diseases, 1987)
- Antibiotic management of surgically treated gangrenous or perforated appendicitis: Comparison of gentamicin and clindamycin versus cefamandole versus cefoperazone (American Journal of Surgery, 1982)
- Sulbactamcefoperazone polyhydroxybutyrateco hydroxyvalerate (PHBV) local antibiotic delivery system: In vivo effectiveness and biocompatibility in the treatment of implantrelated experimental osteomyelitis (Journal of Biomedical Materials Research, 1999)
- Reversal by Cefoperazone of Resistance to Etoposide, Doxorubicin, and Vinblastine in Multidrug Resistant Human Sarcoma Cells (Cancer Research, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cefobid
- Cefoperazone Sodium
- T 1551
- Farmasierra Brand of Cefoperazone Sodium
- Cefoperazone Sodium Salt
- Cefoperazon
- Pfizer Brand of Cefoperazone Sodium
- T-1551
- Cfobis
- T1551
-
SMILESCCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
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InChIKeyGCFBRXLSHGKWDP-UHFFFAOYSA-N
- Pubchem - cefoperazone
- Wikipedia - cefoperazone
Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics. Cefoperazone is also sold as a co-formulation with sulbactam.
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Synthesis
Phenol
+
Reactant
(Friedel-Crafts alkylation)
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cefoperazone
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