| Weight | 481.084 g/mol |
|---|---|
| Formula | C28H37ClN4O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
Clocapramine (47739-98-0, 28058-62-0)
Y-4153 · 3-chlorocarpipramine · 3-chlorocarpipramine dihydrochloride
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- Comparison of Efficacy of Timiperone, a New Butyrophenone Derivative, and Clocapramine in Schizophrenia: A Multiclinic Double-Blind Study (Journal of International Medical Research, 1983)
- Clocapramine-related fatality: Postmortem drug levels in multiple psychoactive drug poisoning (Forensic Science International, 2001)
- A Study on the Pharmacological and Biochemical Profile of Clocapramine (International pharmacopsychiatry, 1982)
- Determination of Clocapramine and Its Metabolites in Plasma by Automated Column-Switching High Performance Liquid Chromatography (Analytical Sciences, 1990)
- A Crossover Study of Clocapramine and Haloperidol in Chronic Schizophrenia (Journal of International Medical Research, 1985)
- Pharmacokinetic study of iminodibenzyl antipsychotic drugs, clocapramine and Y-516 in dog and man. (Psychopharmacology, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Y-4153
- 3-chlorocarpipramine
- 3-chlorocarpipramine dihydrochloride
- 3-chlorocarpipramine dihydrochloride monohydrate
-
SMILESC1CCN(CC1)C2(CCN(CC2)CCCN3C4=CC=CC=C4CCC5=C3C=C(C=C5)Cl)C(=O)N
-
InChIKeyQAZKXHSIKKNOHH-UHFFFAOYSA-N
- Pubchem - Clocapramine
- Wikipedia - clocapramine
Clocapramine (Clofekton, Padrasen), also known as 3-chlorocarpipramine, is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 by Yoshitomi for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been reported to act as an antagonist of the D2, 5-HT2A, 1-adrenergic, and 2-adrenergic receptors, and does not inhibit the reuptake of either serotonin or norepinephrine.
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