| Weight | 547.674 g/mol |
|---|---|
| Formula | C27H37N3O7S |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 11 |
Darunavir (206361-99-1)
Score:
#6 in Virology
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#88 in Microbiology
,
#1044 in Biology
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#1165 in Chemistry
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- Sigma-Aldrich - Darunavir86.30 - 365.50 USD
- Fisher Scientific - Search for Darunavir
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- Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. (The Lancet, 2007)
- Efficacy and safety of once-daily darunavir/ritonavir versus lopinavir/ritonavir in treatment-naive HIV-1-infected patients at week 48 (AIDS, 2008)
- Darunavir: pharmacokinetics and drug interactions. (Antiviral Therapy, 2008)
- Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomised controlled phase III trial (The Lancet, 2007)
- Once-daily darunavir/ritonavir vs. lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysis. (AIDS, 2009)
- Once-daily dolutegravir versus darunavir plus ritonavir in antiretroviral-naive adults with HIV-1 infection (FLAMINGO): 48 week results from the randomised open-label phase 3b study (The Lancet, 2014)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
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InChIKeyCJBJHOAVZSMMDJ-UHFFFAOYSA-N
- Pubchem - Darunavir
- Wikipedia - darunavir
Darunavir (DRV), sold under the brand name Prezista among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It is often used with low doses of ritonavir or cobicistat to increase darunavir levels.
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Darunavir
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