| Weight | 454.447 g/mol |
|---|---|
| Formula | C20H22N8O5 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Amethopterin (60388-53-6)
Methotrexate · Methotrexate Sodium · Mexate
Score:
#377 in Biochemistry
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#1329 in Biology
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#1546 in Chemistry
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- Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. (The New England Journal of Medicine, 2000)
- Infliximab (chimeric anti-tumour necrosis factor monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial (The Lancet, 1999)
- A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. (The New England Journal of Medicine, 1999)
- A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. (The New England Journal of Medicine, 2000)
- Adalimumab, a fully human antitumor necrosis factor monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial (Arthritis & Rheumatism, 2003)
- Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis (Arthritis & Rheumatism, 1998)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Methotrexate
- Methotrexate Sodium
- Mexate
- Dicesium Salt Methotrexate
- Methotrexate, Disodium Salt
- Methotrexate, (DL)-Isomer
- Methotrexate, (D)-Isomer
- Methotrexate Hydrate
- Methotrexate, Sodium Salt
-
SMILESCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
-
InChIKeyFBOZXECLQNJBKD-UHFFFAOYSA-N
- Pubchem - Amethopterin
- Wikipedia - 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid
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