Weight | 435.889 g/mol |
---|---|
Formula | C19H18ClN3O5S |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 4 |
cloxacillin (61-72-3, 642-78-4)
Tegopen · Cloxacillin Sodium · Sodium Cloxacillin
Score:
#105 in Microbiology
,
#1175 in Biology
,
#1343 in Chemistry
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- Photocatalytic degradation of amoxicillin, ampicillin and cloxacillin antibiotics in aqueous solution using UV/TiO2 and UV/H2O2/TiO2 photocatalysis. (Desalination, 2010)
- Degradation of amoxicillin, ampicillin and cloxacillin antibiotics in aqueous solution by the UV/ZnO photocatalytic process (Journal of Hazardous Materials, 2010)
- A sensitive and specific phenotypic assay for detection of metallo--lactamases and KPC in Klebsiella pneumoniae with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin (Clinical Microbiology and Infection, 2011)
- Cloxacillin in the Prophylaxis of Postoperative Infections of the Hip (Journal of Bone and Joint Surgery, American Volume, 1973)
- Effectiveness of Cloxacillin with and without Gentamicin in Short-Term Therapy for Right-Sided Staphylococcus aureus Endocarditis: A Randomized, Controlled Trial (Annals of Internal Medicine, 1996)
- Methicillin (cloxacillin)-resistant Staphylococcus aureus strains isolated from bovine mastitis cases (Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2010)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tegopen
- Cloxacillin Sodium
- Sodium Cloxacillin
- Chloroxacillin
- Syntarpen
-
SMILESCC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
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InChIKeyLQOLIRLGBULYKD-UHFFFAOYSA-N
- Pubchem - cloxacillin
- Wikipedia - cloxacillin
Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. This includes impetigo, cellulitis, pneumonia, septic arthritis, and otitis externa. It is not effective for methicillin-resistant Staphylococcus aureus (MRSA).
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Synthesis
3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
+
6-Aminopenicillanic acid
(Schotten-Baumann amide from acid)
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