| Weight | 680.949 g/mol |
|---|---|
| Formula | C36H60N2O8S |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 12 |
PENBUTOLOL SULFATE (38363-32-5)
Penbutolol · Hoe893d · Hoe 893d
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- In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. (Journal of Pharmacology and Experimental Therapeutics, 1993)
- Long term treatment of moderate hypertension with penbutolol (Hoe 893d). I. Effects on blood pressure, pulse rate, catecholamines in blood and urine, plasma renin activity and urinary aldosterone under basal conditions and following exercise. (European Journal of Clinical Pharmacology, 1975)
- Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol (European Heart Journal, 1983)
- Effects of (-)-tertatolol, (-)-penbutolol and ()-pindolol in combination with paroxetine on presynaptic 5-HT function : an in vivo microdialysis and electrophysiological study (British Journal of Pharmacology, 1999)
- The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients. (Archives internationales de pharmacodynamie et de thrapie, 1975)
- Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain. (Journal of Neurochemistry, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Penbutolol
- Hoe893d
- Hoe 893d
- Hoe-893d
- Penbutolol Sulfate (2:1)
- Betapressin
-
SMILESCC(C)(C)NCC(COC1=CC=CC=C1C2CCCC2)O.CC(C)(C)NCC(COC1=CC=CC=C1C2CCCC2)O.OS(=O)(=O)O
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InChIKeyFEDSNBHHWZEYTP-UHFFFAOYSA-N
- Pubchem - PENBUTOLOL SULFATE
- Wikipedia - penbutolol sulfate
Penbutolol (brand names Levatol, Levatolol, Lobeta, Paginol, Hostabloc, Betapressin) is a medication in the class of beta blockers, used in the treatment of high blood pressure. Penbutolol is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective blocker. Penbutolol is a sympathomimetic drug with properties allowing it to act as a partial agonist at adrenergic receptors.
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