| Weight | 517.564 g/mol |
|---|---|
| Formula | C23H27N5O7S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
piperacillin (61477-96-1, 66258-76-2)
Piperacillin Sodium · Pipracil · Pipercillin
Score:
#228 in Microbiology
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#2201 in Biology
,
#2706 in Chemistry
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- Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection: Clinical Implications of an Extended-Infusion Dosing Strategy (Clinical Infectious Diseases, 2007)
- Piperacillin-tazobactam plus amikacin versus ceftazidime plus amikacin as empiric therapy for fever in granulocytopenic patients with cancer. The International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Cancer. (Antimicrobial Agents and Chemotherapy, 1995)
- False-Positive Galactomannan Platelia Aspergillus Test Results for Patients Receiving Piperacillin-Tazobactam (Clinical Infectious Diseases, 2004)
- False Positive Test for Aspergillus Antigenemia Related to Concomitant Administration of Piperacillin and Tazobactam (The New England Journal of Medicine, 2003)
- Ceftazidime Compared with Piperacillin and Tobramycin for the Empiric Treatment of Fever in Neutropenic Patients with Cancer: A Multicenter Randomized Trial (Annals of Internal Medicine, 1994)
- Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial. (The Lancet, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Piperacillin Sodium
- Pipracil
- Pipercillin
- Pipril
- AHP Brand of Piperacillin Sodium
- Wyeth Brand of Piperacillin Sodium
- Cl 227193
- T1220
- Lederle Brand of Pipracillin Sodium
- Piperacillin Monosodium Salt
- T 1220
- curasan Brand of Piperacillin Sodium
- Piperacillin-ratiopharm
- Hexal Brand of Piperacillin Sodium
- AB Piperacillin
- T-1220
- Fresenius Brand of Piperacillin Sodium
- Piperacillin curasan
- Pipera-hameln
- Cl227193
- ratiopharm Brand of Piperacillin Sodium
- Piperacillin ratiopharm
- Pipera hameln
- Piperacillin Hexal
- Piperacillin Fresenius
- AB-Piperacillin
- Astrapin Brand of Piperacillin Sodium
- Pipcil
- Cl-227193
-
SMILESCCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
-
InChIKeyIVBHGBMCVLDMKU-UHFFFAOYSA-N
- Pubchem - piperacillin
- Wikipedia - piperacillin sodium
Piperacillin is a broad-spectrum -lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into gram-negative bacteria and reduces susceptibility to cleavage by gram-negative beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa.
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Synthesis
Reactant
+
ODIDKWCPMQVCRG-UHFFFAOYSA-N
(Alkylation of primary amines)
Reactant
+
1-Ethylpiperazine-2,3-dione
(Schotten-Baumann amide from acid)
Similar Compounds
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