| Weight | 458.496 g/mol |
|---|---|
| Formula | C21H22N4O6S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Raltitrexed (112887-68-0)
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- Sigma-Aldrich - Search for Raltitrexed
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- Randomized Phase III Study of Cisplatin With or Without Raltitrexed in Patients With Malignant Pleural Mesothelioma: An Intergroup Study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada (Journal of Clinical Oncology, 2005)
- Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer. Tomudex Colorectal Cancer Study Group. (Journal of Clinical Oncology, 1998)
- Final results of a randomised trial comparing Tomudex (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer (Annals of Oncology, 1996)
- Combination of Raltitrexed and Oxaliplatin Is an Active Regimen in Malignant Mesothelioma: Results of a Phase II Study (Journal of Clinical Oncology, 2003)
- Mature results from three large controlled studies with raltitrexed ('Tomudex'). (British Journal of Cancer, 1998)
- Irinotecan plus raltitrexed vs raltitrexed alone in patients with gemcitabine-pretreated advanced pancreatic adenocarcinoma (British Journal of Cancer, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=NC(=O)C2=C(N1)C=CC(=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O
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- Pubchem - Raltitrexed
- Wikipedia - raltitrexed
Raltitrexed (Tomudex, TDX, ZD 1694) is an antimetabolite drug used in cancer chemotherapy. It is an inhibitor of thymidylate synthase, and is manufactured by AstraZeneca.
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