| Weight | 721.86 g/mol |
|---|---|
| Formula | C27H47N9O10S2 |
| Hydrogen Acceptors | 13 |
| Hydrogen Donors | 11 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 10 |
Trypanothione disulfide (96304-42-6)
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- Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases (Biochemistry, 1986)
- "Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease. (Proceedings of the National Academy of Sciences of the United States of America, 1988)
- Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculata (Biochemistry, 1987)
- Synthesis of N-benzyloxycarbonyl-l-cysteinylglycine 3-dimethylaminopropylamide disulfide: A cheap and convenient new assay for trypanothione reductase (Analytical Biochemistry, 1991)
- Solid phase synthesis of trypanothione disulfide (Bioorganic & Medicinal Chemistry Letters, 1994)
- Convenient synthesis of disulfide substrates for trypanothione reductase using polymer-supported reagents (Tetrahedron Letters, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CCNC(=O)CNC(=O)C(CSSCC(C(=O)NCC(=O)NCCCNC1)NC(=O)CCC(C(=O)O)N)NC(=O)CCC(C(=O)O)N
-
InChIKeyLZMSXDHGHZKXJD-UHFFFAOYSA-N
- Pubchem - Trypanothione disulfide
- Wikipedia - Trypanothione
Trypanothione (Mr = 721.86 g/mol) is an unusual form of glutathione containing two molecules of glutathione joined by a spermidine (polyamine) linker. It is found in parasitic protozoa such as leishmania and trypanosomes. These protozoal parasites are the cause of leishmaniasis, sleeping sickness and Chagas' disease.
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