| Weight | 373.368 g/mol |
|---|---|
| Formula | C21H15N3O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Deferasirox (201530-41-8)
Score:
#1265 in Biology
,
#1463 in Chemistry
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- A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia (Blood, 2006)
- Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload (Haematologica, 2006)
- Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions (Blood, 2006)
- A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease (British Journal of Haematology, 2007)
- Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study (European Journal of Haematology, 2007)
- The iron chelator deferasirox protects mice from mucormycosis through iron starvation (Journal of Clinical Investigation, 2007)
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SMILESC1=CC(=C2NC(=C3C=CC=CC3=O)N(N2)C4=CC=C(C=C4)C(=O)O)C(=O)C=C1
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